“Intranasal naloxone is safe and effective for reversing opioid overdose and is now available without prescription,” authors of a JAMA Insights article conclude. “Physicians and
Seven cannabis-related disorders are detailed in a review article, along with the toxic effects of long-term cannabis use. “Cannabis use disorder and heavy or long-term
A population-based cohort study of linked health administrative databases in Ontario shows that older adults had increased serious adverse events (SAEs) when initiation of calcium
Compared with the muscle relaxant tizanidine, the use of baclofen in older adults is associated with a significantly increased risk of falls, researchers report. “The
For empiric treatment of acute infection in hospitalized adults, piperacillin-tazobactam did not increase the incidence of acute kidney injury or death, but cefepime resulted in
A retrospective cohort study among hospitalized veterans with community-acquired pneumonia provides estimates of the individual frequencies of adverse tendon event (TE), Clostridioides difficile infection (CDI), and aortic
Widely used as anti-inflammatory agents, systemic glucocorticoids can increase patients’ susceptibility to opportunistic infections with unintended consequences, according to authors of a review article. “The
Clinical evidence supports effectiveness of cannabis-based medicines in people with multiple sclerosis, chronic pain, and inflammatory bowel disease, and in palliative medicine, according to a
Healthcare workers in the U.S. are at increased risk of dying from drug overdoses compared with non-healthcare workers, a study shows. The results suggest “the
The prohemorrhage interaction of amiodarone with direct oral anticoagulants produces a greater risk for bleeding-related hospitalizations with apixaban or rivaroxaban than with flecainide or sotalol,