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PNN JournalWatch — 5.1.23

Lancet: Quizartinib Plus Chemotherapy in Newly Diagnosed Patients With FLT3-Internal-Tandem-Duplication-Positive Acute Myeloid Leukaemia (QuANTUM-First): A Randomised, Double-Blind, Placebo-Controlled, Phase 3 Trial

Lancet: Efficacy and Safety of Fitusiran Prophylaxis in People With Haemophilia A or Haemophilia B With Inhibitors (ATLAS-INH): A Multicentre, Open-Label, Randomised Phase 3 Trial

Diabetes Care: Metformin and Cancer: Solutions to a Real-World Evidence Failure

Diabetes Care: Cardiovascular Safety in Type 2 Diabetes With Sulfonylureas as Second-Line Drugs: A Nationwide Population-Based Comparative Safety Study

Diabetes Care: Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes

American Journal of Kidney Diseases: Consensus Recommendations for Sick Day Medication Guidance for People With Diabetes, Kidney, or Cardiovascular Disease: A Modified Delphi Process

American Journal of Kidney Diseases: Venglustat, a Novel Glucosylceramide Synthase Inhibitor, in Patients at Risk of Rapidly Progressing ADPKD: Primary Results of a Double-Blind, Placebo-Controlled, Phase 2/3 Randomized Clinical Trial

Source: Lancet, Diabetes Care, American Journal of Kidney Diseases