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Nonvaccination for Influenza Among Patients With CKD

Among 3,692 participants in the Chronic Renal Insufficiency Cohort Study (CRIC), factors associated with not receiving influenza vaccination were younger adults, Black individuals, and adverse social determinants of health, researchers report. “Strategies are needed to address these disparities and reduce barriers to vaccination,” the authors conclude.

Demographic factors, social determinants of health, clinical conditions, and health behaviors of participants in this longitudinal observational study were examined with respect to the receipt of influenza vaccination. The results showed the following: “Between 2009 and 2020, the pooled mean vaccine uptake was 72% (mean age, 66 years; 44% female; 44% Black race). In multivariable models, factors significantly associated with influenza non-vaccination were younger age (aPR, 2.16 [95%CI, 1.85-2.52] for <50 vs. ≥75 years), Black race (1.58 [1.43-1.75] vs. White race), lower education (1.20 [1.04-1.39 for less than high school vs. college graduate]), lower annual household income (1.26 [1.06-1.49] for <$20,000 vs. >$100,000), formerly married status (1.22 [1.09 to 1.35] vs. currently married), and non-employed status (1.13 [1.02-1.24] vs. employed). In contrast, participants with diabetes (aPR, 0.80 [95%CI, 0.73-0.87] vs. no diabetes), chronic obstructive pulmonary disease (COPD) (0.80 [0.70-0.92] vs. no COPD), end-stage kidney disease (0.64 [0.56 to 0.76] vs. estimated glomerular filtration rate ≥60 ml/min/1.73m2), frailty (0.86 [0.74-0.99] vs. no frailty), and ideal physical activity (0.90 [0.82-0.99] vs. physically inactive) were less likely to have non-vaccination status.”

Source: American Journal of Kidney Diseases