Duration of Adjunctive Antidepressant Maintenance in Bipolar I Depression
Continuation of escitalopram or bupropion XL in patients with bipolar I disorder and a recently remitted depressive episode did not show a significant benefit when
Continuation of escitalopram or bupropion XL in patients with bipolar I disorder and a recently remitted depressive episode did not show a significant benefit when
People with type 2 diabetes who previously used 2 noninsulin antihyperglycemic medications showed no significant association between insulin use and all-cause dementia in a cohort
While associated with hepatotoxic effects that led to early trial termination, the oral orexin receptor 2 agonist TAK-994 improved sleepiness and cataplexy in patients with
Clinical benefits were evident in patients with early symptomatic Alzheimer disease after 76 weeks of treatment with the amyloid-targeting monoclonal antibody donanemab, according to findings of
In a phase 3 trial of an investigational oral positive allosteric modulator of the γ-aminobutyric acid type A (GABAA) receptor, zuranolone 50 mg/day significantly improved
Use of menopausal hormone therapy is associated with increased risk of dementia in a nationwide, nested case-control study conducted in Denmark. The relationship held even
In a new recommendation statement, the U.S. Preventive Services Task Force (USPSTF) “concludes with moderate certainty that screening for anxiety disorders in adults, including pregnant and
Deprescribing efforts in community-dwelling persons with dementia (PWD) should include drugs such as PPIs and NSAIDs in addition to CNS agents, investigators conclude. “Community-dwelling PWD
Rather than disease-specific care, integrated care is needed for older veterans involved in the criminal legal system (CLS) because of a high risk of co-occurring mental
In patients referred for electroconvulsive therapy (ECT) for treatment-resistant major depression without psychosis, subanesthetic intravenous ketamine was noninferior to ECT for reducing depressive symptoms by