Risk of Fall and Fracture in Older Adults Taking Baclofen
Compared with the muscle relaxant tizanidine, the use of baclofen in older adults is associated with a significantly increased risk of falls, researchers report. “The
Compared with the muscle relaxant tizanidine, the use of baclofen in older adults is associated with a significantly increased risk of falls, researchers report. “The
In patients aged 49 to 75 years with hand osteoarthritis and synovitis, methotrexate 20 mg once weekly for 6 months had a moderate but potentially
In a placebo-controlled study of 123 patients with generalized pustular psoriasis (GPP) flares, the anti-interleukin-36 receptor monoclonal antibody spesolimab significantly reduced the risk of a
A presenting complaint in 5% of primary care visits, knee pain is commonly the result of osteoarthritis (OA), patellofemoral pain, and meniscal tears, according to
Patients with hand osteoarthritis with an inflammatory phenotype may benefit from methotrexate treatment, a study shows. During 6 months of therapy with methotrexate 20 mg,
In the Sarilumab in Patients with Polymyalgia Rheumatica (SAPHYR) trial, interleukin-6 blockade with the monoclonal antibody “showed significant efficacy in achieving sustained remission and reducing the
Authors of a review article describe how low-grade inflammation in patients with obesity plays a role in the development of other immunological diseases, including cancers
During 2 years of low-dose glucocorticoid therapy for rheumatoid arthritis (RA) in 5 randomized controlled trials, patient weight increased by a modest average of 1
In patients with an inadequate response or intolerance to standard therapy used for the management of juvenile idiopathic arthritis, baricitinib was efficacious with an acceptable
In patients with gout, initiation of treatment with sodium–glucose cotransporter-2 inhibitors (SGLT2is) for diabetes may reduce recurrent flares; reduce gout-primary emergency department (ED) visits and hospitalizations;