In a study of pharmacogenomic variants, researchers found a novel and biologically plausible polymorphism associated with differences in HbA1c levels during metformin monotherapy in African American
Using a case-based approach, authors of a review article describe “synthesizing pharmacogenomics, therapeutic drug monitoring, pharmacokinetics, and pharmacodynamic principles” to address “drug–drug, drug–gene, and drug–drug-gene
A 12-gene pharmacogenetic panel significantly reduced the incidence of clinically relevant adverse drug reactions when implemented across diverse European healthcare systems, researchers report. “Large-scale implementation”
“Could (almost) everything we know about the common genetic effects shared between psychiatric disorders be wrong?” That’s the question asked by an editorialist asked regarding
SGLT2 inhibition that influences risks of type 2 diabetes (T2D) and coronary artery disease (CAD) appears to work through different choline metabolites whose levels are
Biomarker testing can inform selection of therapies for metastatic breast cancer (MBC), according to an updated guideline from the American Society of Clinical Oncology. Evidence
